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doi: 10.3389/fphar.2025.1636538 Received 28 May 2025 Revised 29 October 2025 Accepted 30 October 2025 Published 21 November 2025 Volume 16 - 2025 Edited by Javier Echeverria, University of Santiago, Chile Reviewed by Sara Taha Elazab, Mansoura University, Egypt Glaucia Maria Pastore, State University of Campinas, Brazil Updates Copyright 2025 Yu, Pu, Liu, He, Yang, Chen, Yang, Zhu, Jiang, Luo, Liu, Zhang and He